Clinical trial design challenges in mood disorders /
Poor clinical trial designs result in failed studies wasting hundreds of thousands of dollars in research funds. Poor clinical trial designs limit the rapid advancement of cures for disorders. Yet it's relatively easy to avoid classic poor designs via education about what constitutes good desig...
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| Other Authors: | , , , |
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| Format: | Electronic eBook |
| Language: | English |
| Published: |
London, UK :
Academic Press,
[2015]
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| Subjects: | |
| Online Access: | Full text (Emerson users only) Full text (Emmanuel users only) Full text (NECO users only) Full text (MCPHS users only) Access E-Book Full text (Wentworth users only) |
MARC
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| 245 | 0 | 0 | |a Clinical trial design challenges in mood disorders / |c edited by Mauricio Tohen, Charles L. Bowden, Andrew A. Nierenberg, John R. Geddes. |
| 264 | 1 | |a London, UK : |b Academic Press, |c [2015] | |
| 300 | |a 1 online resource | ||
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| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a <P>Preface</p> <p>Chapter 1: Clinical Trial Design of Maintenance Treatments in Bipolar Disorder Mauricio Tohen</p> <p>Chapter 2: Meta-Analysis of Clinical Trials in Bipolar Disorder John R. Geddes</p> <p>Chapter 3: Effectiveness Trials in Bipolar Disorders Andrew A. Nierenberg</p> <p>Chapter 4: Long-Term Treatment of Mood Disorders: Follow-Up of Acute Treatment Phase Studies Versus Continuation and Maintenance Phase Studies, and Enriched Versus Non-Enriched Designs Willem A. Nolen and Heinz Grunze</p> <p>Chapter 5: The Role of Noninferiority Designs in Bipolar Disorder Clinical Trials Edward Vieta and Núria Cruz</p> <p>Chapter 6: The Use of Mixed Methods in Drug Discovery: Integrating Qualitative Methods into Clinical Trials Michael Berk, Reneé Otmar, Olivia Dean, Lesley Berk and Erin Michalak</p> <p>Chapter 7: Sequential Multiple Assignment Randomized Treatment (SMART): Designs in Bipolar Disorder Clinical Trials Charles L. Bowden and Vivek Singh</p> <p>Chapter 8: Novel Study Designs for Clinical Trials in Mood Disorders Hong Jin Jeon and Maurizio Fava</p> <p>Chapter 9: Rating Scales in Bipolar Disorder Martha Sajatovic, Peijun Chen and Robert C. Young</p> <p>Chapter 10: Clinical Applicability of Results from Drug Trials in Bipolar Disorder -- An Attempt to Shed Light on a Complex Issue Rasmus Wentzer Licht</p> <p>Chapter 11: Clinical Trials in Developing Countries: Challenges in Design, Execution, and Regulation Chittaranjan Andrade and Tim Appaiah</p> | |
| 520 | |a Poor clinical trial designs result in failed studies wasting hundreds of thousands of dollars in research funds. Poor clinical trial designs limit the rapid advancement of cures for disorders. Yet it's relatively easy to avoid classic poor designs via education about what constitutes good design and what the potential outcomes are for any shortcuts taken. The proposed book outlines the classic problems that researchers are faced with in designing clinical trials, whether its money, selection of subjects, regulatory issues etc, and how best to address them for the most definitive and generalizable results. This book is specific to clinical trial issues in psychiatric research, and comes from a task force in Bipolar Research. The contents herein were identified as the most major issues in psychiatric research. Authored by international contributors from academia, industry, regulatory agencies, and advocacy groups, this book summarizes problems in clinical design and the results of same, and whether and how the results can be applied into clinical practice. | ||
| 588 | 0 | |a Vendor-supplied metadata. | |
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Affective disorders. | |
| 650 | 0 | |a Bipolar disorder. | |
| 650 | 1 | 2 | |a Bipolar Disorder |x therapy |
| 650 | 2 | 2 | |a Mood Disorders |x therapy |
| 650 | 2 | 2 | |a Clinical Trials as Topic |
| 650 | 2 | |a Bipolar Disorder | |
| 700 | 1 | |a Tohen, Mauricio, |e editor. | |
| 700 | 1 | |a Bowden, Charles L., |e editor. | |
| 700 | 1 | |a Nierenberg, Andrew A. |q (Andrew Alan), |d 1955- |e editor. |1 https://id.oclc.org/worldcat/entity/E39PCjFkhWm6YhTG3bg9Wt7bVC | |
| 700 | 1 | |a Geddes, John R., |e editor. | |
| 758 | |i has work: |a Clinical trial design challenges in mood disorders (Text) |1 https://id.oclc.org/worldcat/entity/E39PCG94yqyj8yKDrD87RFmdjP |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
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