Modifiable risk factors in the progression of multiple sclerosis : a systematic review of the epidemiology and treatment /

Multiple sclerosis (MS) is the most common progressive disease of the central nervous system in young adults and the cause of serious physical disability in adults of working age. Epidemiologic data suggest that rates of MS vary with demographic and environmental factors. The disease presentation is...

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Bibliographic Details
Main Author: Hempel, Susanne (Author)
Corporate Authors: Quality Enhancement Research Initiative (U.S.), West Los Angeles VA Medical Center. Evidence-Based Synthesis Program Center (Author)
Format: Electronic eBook
Language:English
Published: [Washington, D.C.] : Department of Veterans Affairs (US), December 2015.
Series:Evidence-based synthesis program (Series)
Subjects:
Online Access:http://www.ncbi.nlm.nih.gov/books/NBK424572/

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245 1 0 |a Modifiable risk factors in the progression of multiple sclerosis :  |b a systematic review of the epidemiology and treatment /  |c investigators, Susanne Hempel, Paul Shekelle ; co-investigators, Ning Fu, Elena Estrada, Annie Chen ; research associates, Isomi Miake-Lye, Jessica Beroes, Roberta Shanman, Jeremy Miles. 
264 1 |a [Washington, D.C.] :  |b Department of Veterans Affairs (US),  |c December 2015. 
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520 3 |a Multiple sclerosis (MS) is the most common progressive disease of the central nervous system in young adults and the cause of serious physical disability in adults of working age. Epidemiologic data suggest that rates of MS vary with demographic and environmental factors. The disease presentation is very heterogeneous with diverse clinical manifestations. Progression of MS may vary with modifiable risk factors. This systematic review focused on modifiable risk factors and exposures that are associated with MS progression, and interventions that are directed at modifiable risk factors to delay progression. 
536 |a Prepared for: Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service, Washington, DC 20420. Prepared by: Evidence-based Synthesis Program (ESP) Center, West Los Angeles VA Medical Center, Los Angeles, CA, Paul G. Shekelle, MD, PhD, Director 
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